Sequencing analysis – Communicable Diseases Research

SARS-CoV-2 infection dynamics revealed by wastewater sequencing analysis and deconvolution

Article

Published on 2022-12-202022-11-15
Journal: The Science of the total environment
[Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제,

2FAST2Q: a general-purpose sequence search and counting program for FASTQ files

Article

Published on 2022-10-252023-07-10
Journal: PeerJ
[Category] COVID19(2023년),

[키워드] 2FAST2Q Barcode-seq bioinformatics CRISPRi CRISPRi-seq FASTQ Python Sequencing analysis Tn-seq.
[DOI] 10.7717/peerj.14041 PMC 바로가기

Discovery and characterization of SARS-CoV-2 reactive and neutralizing antibodies from humanized CAMouseHG mice through rapid hybridoma screening and high-throughput single-cell V(D)J sequencing

Article

Published on 2022-09-232022-11-15
Journal: Frontiers in Immunology
[Category] SARS, 변종, 진단, 치료기술,

[키워드] acute respiratory syndrome antibodies antibody antibody humanized mice antibody repertoire Antibody Response assays can be used caused Cell clone complementary coronavirus coronavirus disease cynomolgus macaques death deficiency develop diagnostic effective Efficacy evade fully human antibody Genes humanized humans IGHV6-1 immune response immunization immunized Infection Measures medium mice MOST mutate Neutralizing neutralizing antibody pandemic patients with COVID-19 platform produced Prophylactic Protective reactive reactive and neutralizing antibodies Replication SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RBD binding SARS-CoV-2 virus Sequencing Sequencing analysis significantly single-cell single-cell sequencing. the antibody therapeutic variant Virus neutralization
[DOI] 10.3389/fimmu.2022.992787 PMC 바로가기

Using multiple sampling strategies to estimate SARS-CoV-2 epidemiological parameters from genomic sequencing data

Article

Published on 2022-09-232022-11-16
Journal: Nature Communications
[Category] SARS, 유전자 메커니즘,

Probable Animal-to-Human Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Delta Variant AY.127 Causing a Pet Shop-Related Coronavirus Disease 2019 (COVID-19) Outbreak in Hong Kong

중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 델타 변종 AY.127의 동물 간 전파 가능성이 있어 홍콩에서 애완동물 가게 관련 코로나바이러스 질병 2019(COVID-19) 발생

Article

Published on 2022-08-242022-09-11
Journal: Clinical Infectious Diseases: An Official Publicat
[Category] SARS, 변종,

[키워드] 2 acute respiratory syndrome acute respiratory syndrome coronavirus Analysis anti-SARS-CoV-2 antibody causing Chain Reaction collected conducted Contact coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 CoV COVID-19 COVID-19 outbreak Delta delta variant Delta variant AY.127 demonstrated direct contact dwarf enzyme enzyme immunoassay euthanized female Genome genomes Genomic analysis hamster hamsters Hong Kong Human husband immunoassay infect International investigation Laboratory mammals Mesocricetus nucleotide outbreak pandemic virus Patient patients performed pet Phodopus polymerase chain polymerase chain reaction positive Randomly reported respiratory reverse transcription reverse transcription polymerase chain reaction route RT-PCR SARS SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA Sequencing analysis seropositive severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specimen Spread strain susceptible tested Transmission transmission of SARS-CoV-2 Transmission. transmitted whole genome Whole genome sequencing
[DOI] 10.1093/cid/ciac171 PMC 바로가기 [Article Type] Article

Pulmonary infection by SARS-CoV-2 induces senescence accompanied by an inflammatory phenotype in severe COVID-19: possible implications for viral mutagenesis

SARS-CoV-2에 의한 폐 감염은 심각한 COVID-19에서 염증성 표현형과 함께 노화를 유도합니다: 바이러스 돌연변이 유발 가능성

Article

Published on 2022-08-182022-09-11
Journal: The European Respiratory Journal
[Category] Fulltext, SARS, 진단, 치료기술,

[키워드] accompanied acute respiratory syndrome acute respiratory syndrome coronavirus alveolar analysed angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 APOBEC Apolipoprotein B AT2 Cell cells cellular senescence chronic inflammation Comorbidity Control coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients CXCL8 cytokine Cytokines demonstrated disease DNA damage electron microscopy enzyme Enzymes epithelial exhibited expressed expression extrapulmonary sites H2Ax IL-1β IL-6 IL-6 expression immunocytochemistry immunohistochemistry implication in vitro induce infecting Infection Inflammation inflammatory phenotype Inflammatory response investigated kidney liver lung tissue sample marker Microscopy molecular mechanism multisystemic disease Mutagenesis Non-COVID-19 persistence phenotype progeny proinflammatory promote pulmonary respiratory Respiratory system SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 mutagenesis SARS-CoV-2 mutations SARS-CoV-2 strain SARS-CoV-2 strains SASP senescence senescent cell Sequencing analysis severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe COVID-19 Strains Vero-E6 cell Vero-E6 cells Viral mutagenesis
[DOI] 10.1183/13993003.02951-2021 PMC 바로가기 [Article Type] Article

Bioinformatics analysis of potential pathogenesis and risk genes of immunoinflammation-promoted renal injury in severe COVID-19

Article

Published on 2022-08-162022-11-15
Journal: Frontiers in Immunology
[Category] 바이오마커,

[키워드] activated addition Algorithm ALOX5 Analysis bioinformatics caused CD38 Cell characterized clinical utility correlated COVID-19 COVID-19 patient COVID-19 patients cytokine cytokine receptor dataset dendritic cells enrichment analysis expression expression pattern gene co-expression network Genes glomerular filtration rate HCK identify immune Immune cell Immune cell infiltration Including independent data set indicated Inflammation Inflammatory Injury Interaction involved ischemia-reperfusion injury ITGAX KEGG LYN macrophages MAPK3 Mild Miner moderate NCF4 necroptosis network analysis Neutrophils nomogram Pathogenesis pathway Pathways performed Peripheral blood poor prognosis PPI progression promoted protein-protein interaction random renal renal injury. risk screened SELP Sequencing analysis severe COVID-19 SPI1 STEM TLR2 TLR4 toll-like receptor signaling transcriptomic Viral protein WGCNA
[DOI] 10.3389/fimmu.2022.950076 PMC 바로가기

Genetic basis of sudden death after COVID-19 vaccination in Thailand

Research article

Published on 2022-08-012022-10-05
Journal: Heart Rhythm
[Category] 변종, 유전자 메커니즘, 진단,

Multidrug-resistant OXA-48/CTX-M-15 Klebsiella pneumoniae cluster in a COVID-19 intensive care unit: salient lessons for infection prevention and control during the COVID-19 pandemic

Research article

Published on 2022-08-012022-10-05
Journal: The Journal of hospital infection
[Category] 변종,

[키워드] Appropriate Carbapenemase-producing Enterobacterales Cluster Contact COVID-19 COVID-19 pandemic COVID-19 patients CPE Critical disease doffing donning Escalation finding healthcare healthcare worker hygiene ICU ICUs infection control Infection prevention Infection prevention and control intensive care intensive care patient intensive care unit Intervention isolate Klebsiella pneumoniae measure multidrug-resistant Multidrug-resistant organisms Mutation organism Organisms outbreak outer membrane pathogen Patient patients Personal protective equipment Phylogenetic polymorphism Precaution Prevent Prolonged protocol reduced SARS-CoV-2 screening swab Sequencing Sequencing analysis single nucleotide specimen Surveillance Transmission transmission of SARS-CoV-2 ward with COVID-19
[DOI] 10.1016/j.jhin.2022.05.001 [Article Type] Research article

Using human iPSC-derived kidney organoids to decipher SARS-CoV-2 pathology on single cell level

단일 세포 수준에서 SARS-CoV-2 병리를 해독하기 위해 인간 iPSC 유래 신장 오르가노이드 사용

Article

Published on 2022-07-192022-09-12
Journal: STAR protocols
[Category] COVID19(2023년), MERS, SARS, 진단,